Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406549 | 0.86 | MAPT (0.51) | HPGDLMNAALDH1A1MAPTPOLB | |
| SCHEMBL6409758 | 0.83 | SMN1; SMN2 (0.56) | HPGDLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL6403770 | 0.82 | SMN1; SMN2 (0.44) | HPGDLMNAACMSDALDH1A1KDM4E | |
| SCHEMBL6406156 | 0.80 | GRK6 (0.59) | HPGDLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL16171148 | 0.76 | MEN1 (0.54) | HPGDLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL6408310 | 0.75 | KMT2A (0.52) | HPGDLMNAACMSDALDH1A1KDM4E | |
| SCHEMBL6404584 | 0.75 | RAB9A (0.48) | HPGDLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL6403939 | 0.74 | VCP (0.50) | HPGDLMNAACMSDALDH1A1KDM4E | |
| SCHEMBL6407005 | 0.74 | ACMSD (0.45) | HPGDLMNAACMSDALDH1A1POLB | |
| SCHEMBL6403484 | 0.74 | ADORA3 (0.41) | HPGDLMNAALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | HPGD 835/4885LMNA 4116/4885ACMSD 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.