Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | VCP | P55072 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403551 | 0.84 | ALDH1A1 (0.64) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL6404213 | 0.77 | MEN1 (0.62) | PKMALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6404260 | 0.75 | MEN1 (0.60) | PKMALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6409643 | 0.74 | TP53 (0.65) | PKMALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6405988 | 0.74 | ALDH1A1 (0.57) | PKMALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5334182 | 0.74 | PKM (0.89) | PKMALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6410767 | 0.74 | KDM4E (0.55) | PKMALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6404543 | 0.74 | MAPT (0.64) | PKMALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL6405086 | 0.74 | MAPT (0.61) | ALDH1A1CYP3A4CYP2C9SMN1; SMN2HSD17B10 | |
| SCHEMBL6403977 | 0.73 | LMNA (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | PKM 2155/4885ALDH1A1 720/4885VCP 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.