Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 1/20 | 0.54 |
| ▸ | S100A10 | P60903 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404093 | 0.79 | TSHR (0.74) | ALDH1A1LMNANPSR1MAPTNPC1 | |
| SCHEMBL19281531 | 0.74 | ALDH1A1 (0.46) | ANXA2S100A10ALDH1A1LMNANPSR1 | |
| SCHEMBL16303889 | 0.73 | OPRK1 (0.71) | ANXA2S100A10ALDH1A1LMNANPSR1 | |
| SCHEMBL19289677 | 0.71 | ANXA2 (0.70) | ANXA2S100A10ALDH1A1LMNANPSR1 | |
| SCHEMBL19289675 | 0.69 | ANXA2 (0.58) | ANXA2S100A10ALDH1A1LMNANPSR1 | |
| SCHEMBL13856859 | 0.69 | ALDH1A1 (0.58) | ALDH1A1LMNANPSR1MAPTNPC1 | |
| SCHEMBL11279599 | 0.68 | LMNA (0.57) | ALDH1A1LMNANPSR1MAPTNPC1 | |
| SCHEMBL14793438 | 0.68 | OPRK1 (0.76) | ALDH1A1LMNANPSR1MAPTTSHR | |
| SCHEMBL5336422 | 0.66 | ALPL (0.71) | ALDH1A1LMNAMAPTNPC1HPGD | |
| SCHEMBL20446691 | 0.65 | ALDH1A1 (0.47) | ALDH1A1NPSR1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ANXA2 3914/4885S100A10 4663/4885ALDH1A1 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.