Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6413085 | 1.00 | CYP2D6 (0.50) | CYP2D6CYP2C19CYP1A2ALDH1A1HDAC4 | |
| SCHEMBL6406223 | 1.00 | CYP2D6 (0.50) | CYP2D6CYP2C19CYP1A2ALDH1A1HDAC4 | |
| SCHEMBL6413090 | 1.00 | CYP2D6 (0.50) | CYP2D6CYP2C19CYP1A2ALDH1A1HDAC4 | |
| SCHEMBL6410915 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HDAC4HSD11B1AVPR1ASMN1; SMN2 | |
| SCHEMBL6404844 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HDAC4HSD11B1AVPR1ASMN1; SMN2 | |
| SCHEMBL6406287 | 0.82 | HDAC4 (0.44) | ALDH1A1HDAC4HSD11B1AVPR1ASMN1; SMN2 | |
| SCHEMBL6406294 | 0.82 | HDAC4 (0.44) | ALDH1A1HDAC4HSD11B1AVPR1ASMN1; SMN2 | |
| SCHEMBL6405795 | 0.81 | ALDH1A1 (0.46) | CYP2D6CYP2C19CYP1A2ALDH1A1HDAC4 | |
| SCHEMBL6405792 | 0.81 | ALDH1A1 (0.46) | CYP2D6CYP2C19CYP1A2ALDH1A1HDAC4 | |
| SCHEMBL4830008 | 0.81 | CNR1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-29 | — | — | US | claimed |
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-29 | — | — | US | disclosed |
| US-6852752-B2 | Urea compounds, compositions and methods of use and preparation | VICURON PHARMACEUTICALS INC. (US) | 2005-02-08 | — | — | US | disclosed |
| US-20020119962-A1 | Novel urea compounds, compositions and methods of use and preparation | VICURON HOLDINGS LLC | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | CYP2D6 312/4885CYP2C19 180/4885CYP1A2 181/4885 |
| US-20020119962-A1 | Novel urea compounds, compositions and methods of use and preparation | PDF, UROD, HDHD5 | CYP2D6 3123/4885CYP2C19 2702/4885CYP1A2 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.