Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.51 |
| ▸ | TEK | Q02763 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 4/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 7/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401367 | 0.73 | PDE3B (0.55) | KDREPHB4TEKALDH1A1LMNA | |
| SCHEMBL6405194 | 0.73 | MEN1 (0.47) | KDRCNR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10518939 | 0.71 | PDE3B (0.48) | HRH3MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL6405046 | 0.71 | PDE3B (0.44) | HRH3MEN1 | |
| SCHEMBL20529210 | 0.69 | PDE4B (0.55) | HRH3 | |
| SCHEMBL5569294 | 0.68 | SMN1; SMN2 (0.53) | KDRCNR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6405326 | 0.68 | PKM (0.48) | NPC1MAPTHTT | |
| SCHEMBL6401844 | 0.67 | GRM5 (0.52) | KDRKITFGFR1FLT1KCNJ6 | |
| SCHEMBL17286236 | 0.66 | MEN1 (0.77) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL30949387 | 0.66 | AURKB (0.51) | KDREPHB4TEKCNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583967-B1 | METHOD FOR INHIBITING THE REPLICATION OF HERPES VIRUSES | AICURIS GMBH & CO KG (DE) | 2007-06-27 | — | — | EP | disclosed |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | AICURIS GMBH & CO. KG (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | AICURIS GMBH & CO. KG (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20050059658-A1 | Pyridazinone | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059658-A1 | Pyridazinone | TYMP, TPMT, PDXK | KDR 2962/4885EPHB4 1548/4885TEK 1722/4885 |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | RPL35, PCNA, MCM5 | KDR 2296/4885EPHB4 3470/4885TEK 3479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.