SCHEMBL343359

SCHEMBL343359

CC(=O)c1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
ALDH1A1 P00352 3/20 0.52
RAB9A P51151 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
NPC1 O15118 1/20 0.52
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
HPGD P15428 3/20 0.49
LMNA P02545 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
FFAR4 Q5NUL3 1/20 0.47
STS P08842 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 1/20 0.46
HSD17B1 P14061 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6406510 0.87 MAPT (0.50) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL5563981 0.86 ALDH1A1 (0.50) MAPTALDH1A1SMN1; SMN2NPC1CA12
SCHEMBL4027167 0.81 MAPT (0.61) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL7917653 0.81 ALDH1A1 (0.50) MAPTALDH1A1CA12CA9HPGD
SCHEMBL11050677 0.80 ALDH1A1 (0.44) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL35155 0.79 ALDH1A1 (0.48) ALDH1A1CA12CA9LMNACA1
SCHEMBL601340 0.79 ALDH1A1 (0.58) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL28229 0.79 PTGS2 (0.57) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL40244 0.79 CA2 (0.61) ALDH1A1RAB9ASMN1; SMN2CA12CA9
SCHEMBL7646230 0.79 ALDH1A1 (0.58) MAPTALDH1A1RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 699 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692062-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME Amorepacific Corporation (KR) 2026-02-11 EP claimed
CN-118833938-A Solid slow-release scale inhibitor and preparation method thereof 宝武精高(安徽)科技有限公司 2024-10-25 CN claimed
WO-2024205303-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME (주)아모레퍼시픽 2024-10-03 WO claimed
CN-118352513-B Glass-state MOFs coated positive electrode material, preparation method thereof and secondary battery 江苏蓝固新能源科技有限公司 2024-09-17 CN claimed
CN-118359521-A Preparation method of thioether or thioester compound 中国药科大学 2024-07-19 CN claimed
CN-118352513-A Glass-state MOFs coated positive electrode material, preparation method thereof and secondary battery 江苏蓝固新能源科技有限公司 2024-07-16 CN claimed
WO-2016111658-A1 SYNTHESIS OF THIOSEMICARBAZONE DERIVATIVES COMPRISING SULPHONAMIDE GROUP WITH POTENTIAL ANTICONVULSANT ACTIVITY IYIDOGAN AYSEGUL (TR) 2016-07-14 WO claimed
CN-104678028-A Pretreatment and detection method for biogen amine neurotransmitter and detection kit INST PHARM & TOXICOLOGY AMMS 2015-06-03 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-20260144730-A1 COMPOSITION FOR SKIN ANTI-AGING, SKIN BRIGHTENING OR SKIN REVERSE-AGING CONTAINING AMIDE-BASED COMPOUND AMOREPACIFIC CORPORATION (KR) 2026-05-28 US disclosed
US-12611404-B2 Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides CHEMOCENTRYX, INC. (US) 2026-04-28 US disclosed
US-20260083715-A1 COMPOSITION FOR ENHANCING IMMUNITY CONTAINING AMIDE-BASED COMPOUND AMOREPACIFIC CORPORATION (KR) 2026-03-26 US disclosed
US-12559455-B2 Compound as a UBR box domain ligand AUTOTAC INC. (KR) 2026-02-24 US disclosed
EP-4692062-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME Amorepacific Corporation (KR) 2026-02-11 EP disclosed
EP-0107622-A1 Benzodioxole derivatives, process for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1984-05-02 EP disclosed
US-4443477-A ANTICOAGULANTS, ANTILIPEMIC AGENTS BOEHRINGER MANNHEIM GMBH (DE) 1984-04-17 US disclosed
EP-0087953-A2 Antibacterial 1-normon-2-yl-heterocyclic compounds BEECHAM GROUP PLC (GB) 1983-09-07 EP disclosed
EP-0030030-A1 Derivatives of 2-aminoethanol, processes for their preparation, pharmaceutical compositions containing such compounds and the use the latter CIBA-GEIGY AG (CH) 1981-06-10 EP disclosed
US-4137408-A BACTERICIDES, ANTIBIOTICS WARNER-LAMBERT (US) 1979-01-30 US disclosed
US-4101661-A PENICILLINS, CEPHALOSPORINS WARNER-LAMBERT (US) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144730-A1 COMPOSITION FOR SKIN ANTI-AGING, SKIN BRIGHTENING OR SKIN REVERSE-AGING CONTAINING AMIDE-BASED COMPOUND TYR, ATG13, ARGLU1 MAPT 3260/4885ALDH1A1 1443/4885RAB9A 123/4885
US-20260083715-A1 COMPOSITION FOR ENHANCING IMMUNITY CONTAINING AMIDE-BASED COMPOUND ARG1, MSR1, TLR1 MAPT 4343/4885ALDH1A1 3501/4885RAB9A 231/4885
US-12611404-B2 Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides CCR1, CCR9, CCR8 MAPT 4870/4885ALDH1A1 2034/4885RAB9A 2176/4885
US-12559455-B2 Compound as a UBR box domain ligand UBR4, UBTF, UBQLN1 MAPT 1338/4885ALDH1A1 1486/4885RAB9A 2068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.