SCHEMBL6406980

SCHEMBL6406980

Cc1cc(C(C)(C)C)c(OC(=O)C2CC2COCc2ccc(-c3ccccc3)cc2)c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 8/20 0.43
NAAA Q02083 1/20 0.35
MMP12 P39900 1/20 0.35
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6408295 0.88 FFAR4 (0.40) FFAR4
SCHEMBL6408832 0.83 RXRA (0.35) NAAAMMP12RXRARXRBRXRG
SCHEMBL6412655 0.82 MMP12 (0.34) NAAAMMP12RXRARXRBRXRG
SCHEMBL6407743 0.79 FFAR4 (0.47) FFAR4NAAA
SCHEMBL6412674 0.79 ELANE (0.33)
SCHEMBL6408121 0.78 CHRNA7 (0.35)
SCHEMBL6412514 0.78 CA12 (0.48) FFAR4NAAA
SCHEMBL6406962 0.78 FFAR4 (0.49) FFAR4NAAA
SCHEMBL6454244 0.76 TNFRSF1A (0.31)
SCHEMBL2129348 0.76 VCAM1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 FFAR4 2429/4885NAAA 1503/4885MMP12 2365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.