Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2535725 | 1.00 | LGMN (0.32) | LGMNHRH4GAARAD52CDK1 | |
| SCHEMBL2268408 | 0.99 | LGMN (0.32) | LGMNGAARAD52DPP4 | |
| Hydrochloric Acid SCHEMBL2538013 | 0.87 | HRH4 (0.30) | HRH4 | |
| SCHEMBL2272510 | 0.85 | HRH4 (0.31) | HRH4 | |
| Hydrochloric Acid SCHEMBL4625482 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL2535718 | 0.77 | GAA (0.48) | LGMNGAARAD52CDK1CDK2 | |
| SCHEMBL6544420 | 0.76 | LIPG (0.36) | LGMNDPP4 | |
| SCHEMBL2270047 | 0.76 | GAA (0.49) | LGMNGAARAD52DPP4 | |
| Hydrochloric Acid SCHEMBL3063994 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL2535728 | 0.75 | HRH4 (0.34) | LGMNHRH4GAACDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050257329-A1 | Composition for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one cationic oxidation base, and process using this composition | L'OREAL S.A. (FR) | 2005-11-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050257329-A1 | Composition for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one cationic oxidation base, and process using this composition | KRT18, ADH1C, ADH1A | LGMN 1636/4885HRH4 2559/4885GAA 1852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.