SCHEMBL6407592

SCHEMBL6407592

CC1(C)C(COCc2ccccc2)C1C(=O)OC1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.41
FABP5 Q01469 1/20 0.41
CHRM2 P08172 3/20 0.39
CHRM4 P08173 3/20 0.39
CHRM5 P08912 3/20 0.39
CHRM1 P11229 3/20 0.39
CHRM3 P20309 3/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
MMP13 P45452 1/20 0.39
TSHR P16473 1/20 0.39
SGMS2 Q8NHU3 1/20 0.38
FKBP1A P62942 2/20 0.38
ACHE P22303 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6414745 0.93 EPHX1 (0.44) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL6406894 0.88 CACNA1B (0.43) MMP1MMP2MMP3MMP9MMP13
SCHEMBL3362063 0.83 MMP1 (0.43) MMP1MMP2MMP3MMP9MMP13
SCHEMBL27901906 0.83 FABP7 (0.43) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL1150245 0.81 CHRNB2 (0.45) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL6410838 0.80 FABP7 (0.41) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL6407755 0.80 CHRM2 (0.41) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL11312924 0.79 TSHR (0.42) FABP7FABP5MMP1MMP2MMP3
SCHEMBL3690693 0.79 TSHR (0.42) FABP7FABP5MMP1MMP2MMP3
SCHEMBL6521289 0.79 TSHR (0.42) FABP7FABP5MMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 FABP7 4846/4885FABP5 4727/4885CHRM2 1364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.