SCHEMBL6414745

SCHEMBL6414745

CC1(C)C(COCc2ccc(-c3ccccc3)cc2)C1C(=O)OC1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.44
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
NAAA Q02083 1/20 0.40
CHRM2 P08172 3/20 0.39
CHRM4 P08173 3/20 0.39
CHRM5 P08912 3/20 0.39
CHRM1 P11229 3/20 0.39
CHRM3 P20309 3/20 0.39
FAAH O00519 1/20 0.39
MGLL Q99685 1/20 0.39
FABP7 O15540 1/20 0.39
FABP5 Q01469 1/20 0.39
ABHD6 Q9BV23 1/20 0.39
DAGLA Q9Y4D2 1/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6407592 0.93 FABP7 (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6406894 0.87 CACNA1B (0.43) ALDH1A1LMNARAB9AKMT2A
SCHEMBL6406988 0.85 NAAA (0.40) EPHX1NAAAALDH1A1RAB9A
SCHEMBL6413786 0.81 NAAA (0.42) EPHX1NAAALMNARAB9A
SCHEMBL6406994 0.81 ATM (0.42) EPHX1NAAAALDH1A1RAB9A
SCHEMBL6406124 0.80 PPARA (0.41) NAAA
SCHEMBL6406983 0.80 EPHX1 (0.47) EPHX1SLC6A2SLC6A4NAAACHRM2
SCHEMBL27901906 0.79 FABP7 (0.43) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6408048 0.79 EPHX1 (0.45) EPHX1SLC6A2SLC6A4NAAACHRM2
SCHEMBL6414694 0.78 ALDH1A1 (0.44) ALDH1A1LMNARAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 EPHX1 1885/4885SLC6A2 4346/4885SLC6A4 4167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.