Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012966 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KDM4EGPR119KMT2ACHRM2 | |
| SCHEMBL30058693 | 0.89 | KMT2A (0.43) | ALDH1A1KDM4EGPR119KMT2ACHRM2 | |
| SCHEMBL25199281 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2ACHRM2CHRM1 | |
| SCHEMBL29426713 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EGPR119KMT2ACHRM2 | |
| SCHEMBL16245059 | 0.84 | CYP2D6 (0.55) | ALDH1A1KDM4EGPR119KMT2ACHRM2 | |
| SCHEMBL282240 | 0.83 | GPR119 (0.60) | GPR119KMT2AMMP13 | |
| SCHEMBL3743805 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2ASMN1; SMN2LMNA | |
| SCHEMBL30135960 | 0.83 | MMP13 (0.48) | ALDH1A1KDM4EGPR119KMT2ACHRM2 | |
| SCHEMBL29201731 | 0.83 | GRIN2B (0.53) | ALDH1A1KDM4EMMP2MMP3MMP9 | |
| SCHEMBL3750570 | 0.83 | EPHX2 (0.46) | ALDH1A1KDM4EKMT2ANPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014773-A1 | Therapeutic use | ASTRAZENACA AB (SE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014773-A1 | Therapeutic use | CD4, HLA-DRB1, CD74 | ALDH1A1 315/4885KDM4E 3623/4885GPR119 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.