SCHEMBL6408847

SCHEMBL6408847

COc1ccc(-c2cccc(COCC3C(C(=O)OC(C)(C)C)C3(C)C)c2-c2ccc(OC)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
MMP2 P08253 5/20 0.32
MMP9 P14780 5/20 0.32
MMP12 P39900 4/20 0.32
MMP1 P03956 3/20 0.32
MMP3 P08254 3/20 0.32
MMP13 P45452 3/20 0.32
MMP8 P22894 2/20 0.32
MMP14 P50281 2/20 0.32
MMP16 P51512 2/20 0.32
ENPP1 P22413 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KCNA5 P22460 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6408337 0.87 FFAR1 (0.40) FFAR1FFAR4HDAC4HDAC2HDAC8
SCHEMBL6473664 0.82 FFAR4 (0.39) FFAR1FFAR4HDAC4HDAC2HDAC8
SCHEMBL6408893 0.80 L3MBTL1 (0.41) FFAR1HDAC4MMP2MMP9MMP1
SCHEMBL430965 0.73 ABL1 (0.46) FFAR1FFAR4HDAC4HDAC2HDAC8
SCHEMBL6482211 0.73 FFAR4 (0.42) FFAR1FFAR4HDAC4HDAC2HDAC8
SCHEMBL6406124 0.73 PPARA (0.41) L3MBTL1
SCHEMBL6406120 0.72 L3MBTL1 (0.41) MMP2MMP9MMP1MMP3MMP13
SCHEMBL6409694 0.72 FFAR4 (0.54) FFAR1FFAR4
SCHEMBL6407457 0.71 ALDH1A1 (0.37) L3MBTL1
SCHEMBL6474184 0.71 FFAR4 (0.40) FFAR1FFAR4HDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 FFAR1 1712/4885FFAR4 2429/4885HDAC4 2506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.