Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964910 | 0.88 | ACHE (0.43) | ALDH1A1TSHRMAPK1HTTMAPT | |
| SCHEMBL2958788 | 0.79 | HPGD (0.41) | ALDH1A1NPSR1KDM4EHTTMAPT | |
| SCHEMBL27604333 | 0.69 | DPP4 (0.45) | ALDH1A1TSHRNPSR1DPP4MAPK1 | |
| SCHEMBL2956685 | 0.69 | ADORA2B (0.50) | ALDH1A1KDM4EHTTHIF1APOLB | |
| SCHEMBL27604326 | 0.68 | DCTPP1 (0.35) | ALDH1A1TSHRMAPTLMNAPOLB | |
| SCHEMBL27623275 | 0.68 | ALDH1A1 (0.47) | ALDH1A1TSHRNPSR1DPP4KDM4E | |
| SCHEMBL27604338 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4EHSD17B10HTT | |
| SCHEMBL5718820 | 0.67 | ALDH1A1 (0.83) | ALDH1A1TSHRNPSR1DPP4MAPK1 | |
| SCHEMBL27604336 | 0.66 | ALDH1A1 (0.45) | ALDH1A1TSHRDPP4MAPK1KDM4E | |
| SCHEMBL6417266 | 0.63 | DPP4 (0.40) | ALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1931859-A | New fused imidazole derivative | EISAI CO LTD (JP) | 2007-03-21 | — | — | CN | disclosed |
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |