Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42407 | 0.92 | FBP1 (0.43) | FBP1L3MBTL1PDK1 | |
| SCHEMBL23782857 | 0.88 | FBP1 (0.41) | FBP1L3MBTL1PDK1 | |
| SCHEMBL30489039 | 0.88 | FBP1 (0.41) | FBP1L3MBTL1PDK1 | |
| SCHEMBL12468929 | 0.81 | FBP1 (0.41) | FBP1L3MBTL1PDK1 | |
| SCHEMBL8619562 | 0.73 | FBP1 (0.39) | FBP1L3MBTL1PDK1 | |
| SCHEMBL8751701 | 0.68 | L3MBTL1 (0.35) | FBP1L3MBTL1 | |
| SCHEMBL6411351 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL6036190 | 0.66 | ALDH1A1 (0.33) | L3MBTL1 | |
| SCHEMBL6412386 | 0.66 | NPC1 (0.43) | FBP1L3MBTL1PDK1 | |
| SCHEMBL155319 | 0.66 | NOS1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499616-A1 | HETEROCYCLIC COMPOUNDS | AstraZeneca AB (SE) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003087104-A1 | HETEROCYCLIC COMPOUNDS | ASTRAZENECA AB (SE) | 2003-10-23 | — | — | WO | disclosed |