Sugi Predict

Sugi Predict / Compounds / SCHEMBL42407

SCHEMBL42407

SCHEMBL42407

CCCC[Sn](CCCC)(CCCC)c1nccs1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 5/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ PDK1 Q15118 1/20 0.39
▸ HTR7 P34969 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.32
▸ TSHR P16473 1/20 0.32
▸ NOS1 P29475 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ PLA2G4A P47712 2/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ ADORA2A P29274 1/20 0.31
▸ PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23782857 0.96 FBP1 (0.41) FBP1L3MBTL1PDK1HTR7SMN1; SMN2
SCHEMBL30489039 0.96 FBP1 (0.41) FBP1L3MBTL1PDK1HTR7SMN1; SMN2
SCHEMBL6410067 0.92 FBP1 (0.38) FBP1L3MBTL1PDK1
SCHEMBL12468929 0.88 FBP1 (0.41) FBP1L3MBTL1PDK1HTR7SMN1; SMN2
SCHEMBL8619562 0.79 FBP1 (0.39) FBP1L3MBTL1PDK1HTR7SMN1; SMN2
SCHEMBL6036190 0.72 ALDH1A1 (0.33) L3MBTL1ALDH1A1TSHRHSD17B10
SCHEMBL8141739 0.70 PDPK1 (0.40) L3MBTL1ADORA2A
SCHEMBL1771799 0.69 — —
SCHEMBL577762 0.68 NOS1 (0.36) NOS1
SCHEMBL155319 0.68 NOS1 (0.36) SMN1; SMN2NOS1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1664 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116731293-A Preparation method and application of benzo [1,2-b:4,5-b' ] dithiophene polymer containing asymmetric pi bridge 江汉大学 2023-09-12 — — CN claimed
CN-114058224-B Photo-thermal response super-hydrophobic anti-icing composite coating and preparation method thereof 华南理工大学 2022-10-25 — — CN claimed
CN-114058224-A Photo-thermal response super-hydrophobic anti-icing composite coating and preparation method thereof 华南理工大学 2022-02-18 — — CN claimed
US-20260132126-A1 IMIDAZOLE DERIVATIVES SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 2026-05-14 — — US disclosed
CN-122029166-A Condensed cyclic compound and harmful arthropod control composition containing the same 住友化学株式会社 2026-05-12 — — CN disclosed
US-20260108527-A1 POLO LIKE KINASE 4 INHIBITORS ORIC PHARMACEUTICALS INC (US) 2026-04-23 — — US disclosed
US-12600732-B2 Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway NURIX THERAPEUTICS, INC. (US) 2026-04-14 — — US disclosed
US-12583851-B2 Heteroaryl-substituted pyrazine derivatives as pesticides ELANCO ANIMAL HEALTH GMBH (DE) 2026-03-24 — — US disclosed
US-20260078122-A1 INDAZOLE COMPOUNDS AS PKMYT1 KINASE INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2026-03-19 — — US disclosed
US-20260078131-A1 PYRROLO-PYRIDAZINE INHIBITORS OF JAK2 AJAX THERAPEUTICS INC (US) 2026-03-19 — — US disclosed
EP-4709723-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORPORATION (US) 2026-03-18 — — EP disclosed
WO-1996033194-A1 BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS MODULATORS OF THE GABA A RECEPTOR COMPLEX NEUROSEARCH A/S (DK) 1996-10-24 — — WO disclosed
WO-1996033191-A1 BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS MODULATORS OF THE GABAA RECEPTOR COMPLEX NEUROSEARCH A/S (DK) 1996-10-24 — — WO disclosed
WO-1996026192-A1 ISOXAZOLYL-BENZOYL DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1996-08-29 — — WO disclosed
WO-1996026193-A1 PHENYL DIKETONE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1996-08-29 — — WO disclosed
WO-1996026206-A1 PYRAZOL-4-YL-BENZOYL DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-08-29 — — WO disclosed
WO-1996026200-A1 HERBICIDAL BENZOYL DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1996-08-29 — — WO disclosed
WO-1996022292-A1 TRICYCLIC VASOPRESSIN ANTAGONISTS AMERICAN CYANAMID COMPANY (US) 1996-07-25 — — WO disclosed
WO-1996020184-A1 NAPHTHYL-BENZOXAZEPINES OR -BENZOTHIAZEPINES AS SQUALENE SYNTHETASE INHIBITORS PFIZER INC. (US) 1996-07-04 — — WO disclosed
US-5521173-A TREATING DISEASES CHARACTERIZED BY EXCESS RENAL REABSORPTION OF WATER AMERICAN HOME PRODUCTS CORPORATION (US) 1996-05-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583851-B2 Heteroaryl-substituted pyrazine derivatives as pesticides CBR3, CYCS, CWC15 FBP1 2083/4885L3MBTL1 162/4885PDK1 3239/4885
US-20260108527-A1 POLO LIKE KINASE 4 INHIBITORS PLK4, PLK2, PLK3 FBP1 4049/4885L3MBTL1 2196/4885PDK1 702/4885
US-20260078131-A1 PYRROLO-PYRIDAZINE INHIBITORS OF JAK2 JAK2, JAK1, JAK3 FBP1 4091/4885L3MBTL1 3189/4885PDK1 1530/4885
US-20260132126-A1 IMIDAZOLE DERIVATIVES ADRA1A, ADRA1D, ADRB1 FBP1 1567/4885L3MBTL1 880/4885PDK1 2710/4885
US-20260078122-A1 INDAZOLE COMPOUNDS AS PKMYT1 KINASE INHIBITORS PKN3, PKMYT1, IP6K3 FBP1 1980/4885L3MBTL1 687/4885PDK1 378/4885
US-12600732-B2 Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway BTK, BCL9, BCL9L FBP1 3790/4885L3MBTL1 1491/4885PDK1 2926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.