SCHEMBL6410192

SCHEMBL6410192

COC(=O)C1C(C)C1COCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 6/20 0.42
EPHX1 P07099 1/20 0.40
RAB9A P51151 2/20 0.39
MAPT P10636 1/20 0.39
SMPD1 P17405 1/20 0.39
POLB P06746 1/20 0.38
NPC1 O15118 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6407675 0.92 POLB (0.42) POLBMEN1KMT2A
SCHEMBL6414765 0.88 NAAA (0.43) NAAAEPHX1RAB9ANPC1
SCHEMBL6413630 0.87 ATM (0.43) NAAAEPHX1RAB9ANPC1
SCHEMBL6406976 0.86 PPARA (0.41) NAAA
SCHEMBL6415827 0.84 HTT (0.45) RAB9AMAPTPOLBNPC1
SCHEMBL6408048 0.82 EPHX1 (0.45) NAAAEPHX1MEN1KMT2A
SCHEMBL6412245 0.79 FABP7 (0.44) KMT2A
SCHEMBL20517351 0.79 FABP7 (0.44) KMT2A
SCHEMBL6406896 0.78 FABP7 (0.43) MEN1KMT2A
SCHEMBL6408832 0.78 RXRA (0.35) NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 NAAA 1503/4885EPHX1 1885/4885RAB9A 3057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.