SCHEMBL6408048

SCHEMBL6408048

CC1C(COCc2ccc(-c3ccccc3)cc2)C1C(=O)OC1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.45
FABP7 O15540 1/20 0.44
FABP5 Q01469 1/20 0.44
ABHD6 Q9BV23 3/20 0.41
DAGLA Q9Y4D2 3/20 0.41
NAAA Q02083 1/20 0.40
CHRM2 P08172 2/20 0.40
CHRM4 P08173 2/20 0.40
CHRM5 P08912 2/20 0.40
CHRM1 P11229 2/20 0.40
CHRM3 P20309 2/20 0.40
HRH3 Q9Y5N1 1/20 0.40
FAAH O00519 1/20 0.40
MGLL Q99685 1/20 0.40
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
ENPP2 Q13822 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6410593 0.93 FABP7 (0.48) FABP7FABP5ABHD6DAGLACHRM2
SCHEMBL6411945 0.85 CACNA1B (0.43) FABP7FABP5ALDH1A1KMT2ASLC6A2
SCHEMBL6410192 0.82 NAAA (0.42) EPHX1NAAAMEN1KMT2A
SCHEMBL6414765 0.81 NAAA (0.43) EPHX1ABHD6DAGLANAAAHRH3
SCHEMBL6406983 0.81 EPHX1 (0.47) EPHX1FABP7FABP5ABHD6DAGLA
SCHEMBL6413630 0.80 ATM (0.43) EPHX1NAAAHRH3TSHR
SCHEMBL6406976 0.79 PPARA (0.41) NAAA
SCHEMBL6414745 0.79 EPHX1 (0.44) EPHX1FABP7FABP5ABHD6DAGLA
SCHEMBL6411610 0.78 FABP7 (0.47) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL6411232 0.78 ALDH1A1 (0.45) MEN1ALDH1A1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 EPHX1 1885/4885FABP7 4846/4885FABP5 4727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.