Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | VCP | P55072 | 9/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403317 | 0.96 | PKM (1.00) | PKMALDH1A1LMNAL3MBTL1VCP | |
| SCHEMBL6405019 | 0.93 | PKM (0.87) | PKMALDH1A1LMNAL3MBTL1VCP | |
| SCHEMBL6403187 | 0.88 | VCP (0.86) | PKMALDH1A1LMNAVCPSMN1; SMN2 | |
| SCHEMBL6403407 | 0.83 | PKM (0.74) | PKMALDH1A1LMNAL3MBTL1VCP | |
| SCHEMBL6405241 | 0.82 | L3MBTL1 (0.84) | PKMALDH1A1LMNAL3MBTL1VCP | |
| SCHEMBL6405274 | 0.82 | GAA (0.74) | PKMALDH1A1LMNAL3MBTL1VCP | |
| SCHEMBL6404082 | 0.80 | RXRA (0.74) | PKMALDH1A1LMNAL3MBTL1VCP | |
| SCHEMBL6408255 | 0.76 | POLB (0.73) | PKMALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL6402672 | 0.75 | DGAT1 (0.57) | PKMALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL11887417 | 0.73 | KMT2A (0.80) | ALDH1A1LMNAL3MBTL1VCPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | PKM 2155/4885ALDH1A1 720/4885LMNA 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.