Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.77 |
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.77 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.77 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 7/20 | 0.67 |
| ▸ | CA2 | P00918 | 7/20 | 0.67 |
| ▸ | VDR | P11473 | 2/20 | 0.61 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.60 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269524 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL14485302 | 0.92 | GPBAR1 (0.85) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19549232 | 0.92 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19577237 | 0.92 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19549236 | 0.92 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL18199508 | 0.91 | GPBAR1 (0.81) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL25658157 | 0.91 | GPBAR1 (0.81) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL14485375 | 0.89 | GPBAR1 (0.78) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL1977807 | 0.89 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19577615 | 0.89 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256093-A1 | Branched polyamine steroid derivatives | LEO PHARMA (DK) | 2005-11-17 | — | — | US | claimed |
| US-20250002450-A1 | CATIONIC STEROID COMPOUNDS, METHOD OF OBTAINING THEREOF, FORMULATIONS COMPRISING THEREOF AND THEIR USES | UNIVERSIDADE DO PORTO (PT) | 2025-01-02 | — | — | US | disclosed |
| EP-4444422-A1 | CATIONIC STEROID COMPOUNDS, METHOD OF OBTAINING THEREOF, FORMULATIONS COMPRISING THEREOF AND THEIR USES | Universidade Do Porto (PT) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023105494-A1 | CATIONIC STEROID COMPOUNDS, METHOD OF OBTAINING THEREOF, FORMULATIONS COMPRISING THEREOF AND THEIR USES | UNIVERSIDADE DO PORTO (PT) | 2023-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256093-A1 | Branched polyamine steroid derivatives | SRM, SMS, NR5A1 | GPBAR1 91/4885SLC10A2 1123/4885ABCC4 2641/4885 |
| US-20250002450-A1 | CATIONIC STEROID COMPOUNDS, METHOD OF OBTAINING THEREOF, FORMULATIONS COMPRISING THEREOF AND THEIR USES | CYP17A1, HSD17B7, NR3C2 | GPBAR1 1185/4885SLC10A2 108/4885ABCC4 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.