Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.33 |
| ▸ | PGR | P06401 | 4/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887533 | 0.74 | CA1 (0.42) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6094467 | 0.71 | FABP4 (0.34) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5887535 | 0.68 | MAPT (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7937672 | 0.65 | FABP4 (0.36) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6414538 | 0.65 | FABP4 (0.51) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3687291 | 0.63 | L3MBTL1 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4746858 | 0.62 | FABP4 (0.68) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4747454 | 0.61 | FABP4 (0.66) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7517048 | 0.61 | FABP4 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL24441746 | 0.61 | SIGMAR1 (0.42) | POLBTSHRDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515973-A1 | PORPHYRIN-POLYAMINE CONJUGATES FOR CANCER THERAPY | Cellgate Inc. (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004002991-A1 | PORPHYRIN-POLYAMINE CONJUGATES FOR CANCER THERAPY | CELLGATE, INC. (US) | 2004-01-08 | — | — | WO | disclosed |