Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.35 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517197 | 0.73 | FABP4 (0.34) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL4746886 | 0.71 | NR3C1 (0.36) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL6413864 | 0.65 | CA1 (0.39) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL5887533 | 0.63 | CA1 (0.42) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL5887535 | 0.63 | MAPT (0.46) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL14454650 | 0.63 | RAPGEF4 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3867855 | 0.62 | CA1 (0.59) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL7511658 | 0.62 | FABP4 (0.61) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL7517048 | 0.62 | FABP4 (0.61) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL5963342 | 0.61 | FABP4 (0.76) | FABP4CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | disclosed |