Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 8/20 | 0.46 |
| ▸ | THRB | P10828 | 8/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12949905 | 0.87 | THRA (0.51) | THRATHRBLMNAKDM4EMAPK1 | |
| SCHEMBL3911899 | 0.83 | IGF1R (0.52) | THRATHRBHSP90AA1HSP90AB1 | |
| SCHEMBL1260613 | 0.83 | ALOX15 (0.57) | ADRB2LMNAKDM4EMAPK1SLC22A1 | |
| SCHEMBL1860686 | 0.81 | CNR1 (0.60) | THRATHRBKDM4EDRD2DRD1 | |
| SCHEMBL9502934 | 0.81 | GRIN2D (0.48) | THRATHRBHSP90AA1HSP90AB1 | |
| SCHEMBL8498153 | 0.80 | ESR1 (0.57) | TYRADRB2LMNAKDM4EMAPK1 | |
| SCHEMBL6419829 | 0.79 | GSR (0.53) | TYRLMNACA1CA2SLC6A2 | |
| SCHEMBL4392926 | 0.79 | THRA (0.55) | THRATHRBLMNAKDM4EMAPK1 | |
| SCHEMBL20920805 | 0.79 | IGF1R (0.53) | THRATHRBADRB2ADORA3ADRA2B | |
| SCHEMBL6417134 | 0.79 | IGF1R (0.47) | THRATHRBKDM4EHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2005-12-15 | — | — | US | disclosed |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | TYR 2/4885THRA 3811/4885THRB 4357/4885 |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | TYR 2/4885THRA 3811/4885THRB 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.