Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | CTSD | P07339 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69437 | 0.83 | HSD17B10 (0.67) | ALDH1A1TDP1CTSDHSD17B10TSHR | |
| SCHEMBL19737269 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TDP1CTSDHSD17B10TSHR | |
| Hydrazobenzene SCHEMBL51179 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TDP1CTSDHSD17B10TSHR | |
| SCHEMBL9274501 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1HSD17B10TSHRPTGS2 | |
| Hydrazobenzene SCHEMBL28199819 | 0.78 | ALDH1A1 (0.92) | ALDH1A1TDP1CTSDHSD17B10TSHR | |
| SCHEMBL4050842 | 0.74 | ALDH1A1 (0.74) | ALDH1A1HSD17B10CYP3A4LMNACYP1A2 | |
| SCHEMBL751586 | 0.74 | SMN1; SMN2 (0.74) | TSHRLMNAMAPTMEN1KMT2A | |
| Hydrazobenzene SCHEMBL29066354 | 0.73 | ALDH1A1 (0.80) | ALDH1A1TDP1CTSDHSD17B10TSHR | |
| SCHEMBL21764766 | 0.72 | ALDH1A1 (0.79) | ALDH1A1TDP1CTSDHSD17B10TSHR | |
| SCHEMBL22620524 | 0.71 | ALDH1A1 (0.81) | ALDH1A1TDP1CTSDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075374-A1 | Sulfonyl aryl or heteroaryl hydroxamic acid compounds | PHARMACIA CORPORATION | 2005-04-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075374-A1 | Sulfonyl aryl or heteroaryl hydroxamic acid compounds | MMP1, MMP2, MMP3 | ALDH1A1 925/4885TDP1 2291/4885CTSD 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.