Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409629 | 0.89 | KDM5A (0.47) | ACLYKDM5AHSPA5POLBMEN1 | |
| SCHEMBL6408135 | 0.87 | KCNMA1 (0.55) | KCNMA1HSPA5POLBMEN1KMT2A | |
| SCHEMBL6407658 | 0.85 | CA1 (0.48) | ACLYKCNMA1HSPA5POLBMAPT | |
| SCHEMBL6410312 | 0.82 | KCNMA1 (0.52) | ACLYKCNMA1HSPA5POLBKDM4E | |
| SCHEMBL6415342 | 0.82 | HSPA5 (0.47) | KCNMA1HSPA5POLBMEN1KMT2A | |
| SCHEMBL6410292 | 0.82 | HSPA5 (0.62) | ACLYHSPA5POLBMEN1KMT2A | |
| SCHEMBL6409044 | 0.81 | KMT2A (0.50) | ACLYKCNMA1HSPA5POLBMEN1 | |
| SCHEMBL6408459 | 0.81 | ACLY (0.59) | ACLYKCNMA1KDM4E | |
| SCHEMBL6407663 | 0.80 | NPC1 (0.50) | KCNMA1HSPA5POLBMEN1KMT2A | |
| SCHEMBL6410608 | 0.79 | NPC1 (0.53) | KCNMA1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | claimed |
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | ACLY 2109/4885KCNMA1 2149/4885KDM5A 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.