Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GPR88 | Q9GZN0 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1346573 | 0.94 | POLB (0.51) | POLBTDP1L3MBTL1GPR88LMNA | |
| SCHEMBL14599980 | 0.88 | LMNA (0.64) | POLBGPR88LMNAMMP9MMP8 | |
| SCHEMBL6414796 | 0.88 | LMNA (0.64) | POLBGPR88LMNAMMP9MMP8 | |
| SCHEMBL9861070 | 0.86 | LMNA (0.62) | POLBTDP1L3MBTL1GPR88LMNA | |
| SCHEMBL9629526 | 0.85 | MEN1 (0.50) | POLBTDP1L3MBTL1GPR88LMNA | |
| SCHEMBL14599721 | 0.85 | GPR88 (0.59) | POLBGPR88LMNAAKR1C3AKR1C2 | |
| SCHEMBL11595380 | 0.84 | POLB (0.51) | POLBTDP1L3MBTL1GPR88LMNA | |
| SCHEMBL9000258 | 0.84 | RARB (0.65) | POLBGPR88LMNAPTGS2MMP9 | |
| SCHEMBL7609893 | 0.83 | POLB (0.51) | POLBTDP1L3MBTL1GPR88LMNA | |
| SCHEMBL7403967 | 0.82 | GPR88 (0.59) | L3MBTL1GPR88LMNAAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42221-E1 | Polymerizable liquid crystal composition and polymer thereof | CHISSO CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| US-7393569-B2 | Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules | CHISSO CORPORATION (JP) | 2008-07-01 | — | — | US | disclosed |
| US-7378135-B2 | Polymerizable liquid crystal composition and optically anisotropic thin film | CHISSO CORPORATION (JP) | 2008-05-27 | — | — | US | disclosed |
| US-20060278851-A1 | Polymerizable liquid crystal composition and polymer thereof | CHISSO CORPORATION AND CHISSO PETROCHEMICAL CORPORATION | 2006-12-14 | — | — | US | disclosed |
| US-20060222784-A1 | Polymerizable liquid crystal composition and optically anisotropic thin film | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060278851-A1 | Polymerizable liquid crystal composition and polymer thereof | NCAPD2, LANCL2, TAF1 | POLB 3734/4885TDP1 927/4885L3MBTL1 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.