Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.56 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599980 | 0.96 | LMNA (0.64) | RARBLMNATP53TSHRPOLB | |
| SCHEMBL6414796 | 0.96 | LMNA (0.64) | RARBLMNATP53TSHRPOLB | |
| SCHEMBL9861070 | 0.94 | LMNA (0.62) | RARBLMNATP53TSHRPOLB | |
| SCHEMBL14599721 | 0.91 | GPR88 (0.59) | LMNAPTGS2TP53TSHRPOLB | |
| SCHEMBL7054030 | 0.87 | PTGS2 (0.57) | RARBLMNAPTGS2TP53TSHR | |
| SCHEMBL27859167 | 0.85 | TP53 (0.59) | RARBLMNATP53TSHRPOLB | |
| SCHEMBL8403335 | 0.85 | GPR88 (0.59) | RARBLMNAPTGS2GPR88 | |
| SCHEMBL7403967 | 0.85 | GPR88 (0.59) | RARBLMNAPTGS2GPR88 | |
| SCHEMBL10335970 | 0.84 | RARB (0.59) | RARBLMNATP53TSHRPOLB | |
| SCHEMBL1532485 | 0.84 | POLB (0.53) | RARBLMNAPTGS2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5507975-A | CONTAINING COMPOUND HAVING OPTICALLY ACTIVE LACTONE GROUP | SHARP KABUSHIKI KAISHA (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0442504-B1 | Ferroelectric liquid crystal device | SHARP KK (JP) | 1995-05-03 | — | — | EP | disclosed |
| EP-0384432-B1 | Liquid crystalline compound and use thereof | DAISO CO LTD (JP) | 1993-12-08 | — | — | EP | disclosed |
| EP-0421438-B1 | FERROELECTRIC LIQUID CRYSTAL DEVICE | SHARP KABUSHIKI KAISHA (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-5151214-A | A pair of substrates with an orientation controlling layer and a liquid crystal layer | SHARP KABUSHIKI KAISHA (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0442504-A2 | Ferroelectric liquid crystal device | SHARP KABUSHIKI KAISHA (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0421438-A2 | Ferroelectric liquid crystal device | SHARP KABUSHIKI KAISHA (JP) | 1991-04-10 | — | — | EP | disclosed |