Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599980 | 0.98 | LMNA (0.64) | LMNAGPR88TP53TSHRPOLB | |
| SCHEMBL6414796 | 0.98 | LMNA (0.64) | LMNAGPR88TP53TSHRPOLB | |
| SCHEMBL14599721 | 0.97 | GPR88 (0.59) | LMNAGPR88TP53TSHRPOLB | |
| SCHEMBL9000258 | 0.94 | RARB (0.65) | LMNAGPR88TP53TSHRPOLB | |
| SCHEMBL8403335 | 0.90 | GPR88 (0.59) | LMNAGPR88RARBL3MBTL1AKR1C3 | |
| SCHEMBL7403967 | 0.90 | GPR88 (0.59) | LMNAGPR88RARBL3MBTL1AKR1C3 | |
| SCHEMBL27859167 | 0.87 | TP53 (0.59) | LMNAGPR88TP53TSHRPOLB | |
| SCHEMBL9591536 | 0.87 | AKR1C3 (0.74) | LMNAGPR88TSHRPOLBAKR1C3 | |
| SCHEMBL1532485 | 0.86 | POLB (0.53) | LMNAGPR88TP53TSHRPOLB | |
| SCHEMBL9585079 | 0.86 | AKR1C3 (0.72) | LMNATP53TSHRPOLBMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240665-B1 | PROCESS FOR REFINING 2-(ARYL SUBSTITUTED) PROPIONIC ACID OR ITS SALTS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-05-29 | — | — | EP | claimed |
| EP-0232863-B1 | PROCESS FOR PRODUCING AN (ARYL SUBSTITUTED) CARBOXYLIC ACID OR ITS SALT | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-09-26 | — | — | EP | claimed |
| US-4814494-A | OXIDATION, HYDROGENATION | NIPPON PETROCHEMICALS COMPANY, LTD. (JP) | 1989-03-21 | — | — | US | claimed |
| US-4709089-A | DEHALOGENATION | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | claimed |
| EP-0240665-A1 | Process for refining 2-(aryl substituted) propionic acid or its salts | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-10-14 | — | — | EP | claimed |
| EP-0232863-A1 | Process for producing an (aryl substituted) carboxylic acid or its salt | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-08-19 | — | — | EP | claimed |
| EP-0240665-B1 | PROCESS FOR REFINING 2-(ARYL SUBSTITUTED) PROPIONIC ACID OR ITS SALTS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0232863-B1 | PROCESS FOR PRODUCING AN (ARYL SUBSTITUTED) CARBOXYLIC ACID OR ITS SALT | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4814494-A | OXIDATION, HYDROGENATION | NIPPON PETROCHEMICALS COMPANY, LTD. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4709089-A | DEHALOGENATION | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0240665-A1 | Process for refining 2-(aryl substituted) propionic acid or its salts | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-10-14 | — | — | EP | disclosed |
| EP-0232863-A1 | Process for producing an (aryl substituted) carboxylic acid or its salt | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-08-19 | — | — | EP | disclosed |