Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15520448 | 0.89 | ALDH1A1 (0.60) | LMNAPDE4DALOX12ALDH1A1KDM4E | |
| SCHEMBL6420806 | 0.89 | ALDH1A1 (0.51) | LMNAPDE4DALDH1A1KMT2APOLB | |
| SCHEMBL28650933 | 0.86 | THRB (0.49) | LMNAPDE4DTP53ALDH1A1KDM4E | |
| SCHEMBL6422295 | 0.86 | KMT2A (0.65) | LMNAPDE4DTP53ALOX12ALDH1A1 | |
| SCHEMBL16112407 | 0.84 | SMN1; SMN2 (0.59) | LMNATP53ALDH1A1KDM4EHPGD | |
| SCHEMBL6415533 | 0.84 | LMNA (0.54) | LMNAPDE4DTP53ALOX12ALDH1A1 | |
| SCHEMBL4981925 | 0.83 | LMNA (0.56) | LMNAPDE4DTP53ALOX12ALDH1A1 | |
| SCHEMBL22896894 | 0.83 | LMNA (0.56) | LMNAPDE4DTP53ALOX12ALDH1A1 | |
| SCHEMBL19475586 | 0.83 | ALDH1A1 (0.59) | LMNAPDE4DTP53ALOX12ALDH1A1 | |
| SCHEMBL6414140 | 0.83 | ALDH1A1 (0.53) | LMNAPDE4DTP53ALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AVENTIS PHARMA S. A. (FR) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AHR, NQO1, ARNT | LMNA 2233/4885PDE4D 3227/4885TP53 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.