Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504374 | 0.80 | LMNA (0.59) | LMNATDP1PKMNPC1RAB9A | |
| SCHEMBL2695470 | 0.80 | LMNA (0.62) | LMNATDP1PKMNPC1RAB9A | |
| SCHEMBL21733186 | 0.76 | ALDH1A1 (0.57) | LMNATDP1PKMNPC1RAB9A | |
| SCHEMBL16247754 | 0.76 | LMNA (0.57) | LMNATDP1PKMNPC1RAB9A | |
| SCHEMBL137486 | 0.76 | TDP1 (0.83) | LMNATDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL24325565 | 0.75 | LMNA (0.65) | LMNATDP1PKMNPC1RAB9A | |
| SCHEMBL7603210 | 0.74 | TDP1 (0.68) | LMNATDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL13292516 | 0.74 | TDP1 (0.79) | LMNATDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL547137 | 0.74 | TDP1 (0.79) | LMNATDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL28286830 | 0.74 | TDP1 (0.79) | LMNATDP1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050249692-A1 | Polymer, cosmetic composition comprising same and method of preparing same | MITSUBISHI CHEMICAL CORPORATION | 2005-11-10 | — | — | US | disclosed |
| EP-1462463-A1 | Guanidin-group containing polymer, cosmetic employing same and method of preparing same | Mitsubishi Chemical Corporation (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-0805674-B1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORP (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-20020172655-A1 | Cosmetic-use polymer, cosmetic employing same, and method of preparing same | MITSUBISHI CHEMICAL CORPORATION | 2002-11-21 | — | — | US | disclosed |
| EP-1236744-A2 | Guanidin-group containing polymer, cosmetic employing same and method of preparing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6348200-B1 | OXYALKYLAMIDE OR AMINE DERIVATIVES;AT LEAST ONE OF POLYHYDRIC ALCOHOLS, OR VEGETABLE EXTRACTS, OR ORGANIC ACIDS; IMPROVES WATER-RETAINING ABILITY OF HORNY LAYER, CURES ROUGHNESS AND PREVENTS WRINKLES | KAO CORPORATION (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6187955-B1 | A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS | KAO CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| US-5723133-A | GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING | KAO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0805674-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | Kao Corporation (JP) | 1997-11-12 | — | — | EP | disclosed |
| WO-1997014401-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORPORATION (JP) | 1997-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020172655-A1 | Cosmetic-use polymer, cosmetic employing same, and method of preparing same | DNMT1, PRMT1, JMJD6 | LMNA 1665/4885TDP1 369/4885PKM 1415/4885 |
| US-20050249692-A1 | Polymer, cosmetic composition comprising same and method of preparing same | DNMT1, TET2, H1-0 | LMNA 743/4885TDP1 669/4885PKM 1216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.