Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4194169 | 0.93 | HDAC4 (0.34) | HDAC4HDAC7HDAC5KMT2AGAA | |
| SCHEMBL38665521 | 0.79 | HDAC4 (0.49) | HDAC4HDAC7HDAC5KMT2AGAA | |
| SCHEMBL6254107 | 0.77 | HDAC4 (0.51) | HDAC4HDAC7HDAC5KMT2AGAA | |
| SCHEMBL38664478 | 0.77 | HDAC4 (0.51) | HDAC4HDAC7HDAC5KMT2AGAA | |
| SCHEMBL4192299 | 0.74 | HDAC4 (0.40) | HDAC4HDAC7HDAC5KMT2AGAA | |
| SCHEMBL38662000 | 0.74 | HDAC4 (0.44) | HDAC4HDAC7HDAC5KMT2AGAA | |
| SCHEMBL3896596 | 0.73 | KMT2A (0.34) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL38664716 | 0.72 | HDAC4 (0.49) | HDAC4HDAC7HDAC5KMT2AGAA | |
| SCHEMBL38664713 | 0.72 | HDAC4 (0.46) | HDAC4HDAC7HDAC5KMT2AGAA | |
| SCHEMBL4178444 | 0.71 | HDAC4 (0.37) | HDAC4HDAC7HDAC5KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11932603-B2 | Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20220227711-A1 | HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2022-07-21 | — | — | US | disclosed |
| US-11332445-B2 | Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20200190037-A1 | HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2020-06-18 | — | — | US | disclosed |
| EP-3019575-B1 | HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2018-12-19 | — | — | EP | disclosed |
| EP-3067345-B1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2018-09-05 | — | — | EP | disclosed |
| US-20170320830-A1 | HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2017-11-09 | — | — | US | disclosed |
| US-9575062-B2 | Zwitterion-containing acridinium compounds | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2017-02-21 | — | — | US | disclosed |
| EP-3067345-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | Siemens Healthcare Diagnostics Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| EP-2501681-B1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2016-05-25 | — | — | EP | disclosed |
| EP-2501681-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | Siemens Healthcare Diagnostics Inc. (US) | 2012-09-26 | — | — | EP | disclosed |
| US-20120225497-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2012-09-06 | — | — | US | disclosed |
| EP-2074101-B1 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2012-08-08 | — | — | EP | disclosed |
| US-8119422-B2 | Stable acridinium esters with fast light emission | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2012-02-21 | — | — | US | disclosed |
| WO-2011060228-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| US-7785904-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20100099077-A1 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-20080014660-A1 | High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity | BAYER HEALTHCARE LLC | 2008-01-17 | — | — | US | disclosed |
| US-7309615-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) | 2007-12-18 | — | — | US | disclosed |
| US-20050221390-A1 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | BAYER HEALTHCARE LLC (US) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190037-A1 | HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION | ACR, HACD3, FCGR3B | HDAC4 4063/4885HDAC7 2726/4885HDAC5 4539/4885 |
| US-20170320830-A1 | HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION | ACR, HACD3, FCGR3B | HDAC4 4063/4885HDAC7 2726/4885HDAC5 4539/4885 |
| US-11332445-B2 | Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission | ACR, HACD3, FCGR3B | HDAC4 4063/4885HDAC7 2726/4885HDAC5 4539/4885 |
| US-20220227711-A1 | HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION | ACR, HACD3, FCGR3B | HDAC4 4063/4885HDAC7 2726/4885HDAC5 4539/4885 |
| US-20120225497-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | ACR, SSB, FCGR3B | HDAC4 3376/4885HDAC7 4037/4885HDAC5 3273/4885 |
| US-20100099077-A1 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | ACR, NAALAD2, CES2 | HDAC4 3172/4885HDAC7 3247/4885HDAC5 3603/4885 |
| US-11932603-B2 | Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission | ACR, HACD3, FCGR3B | HDAC4 4063/4885HDAC7 2726/4885HDAC5 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.