Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL1893593 | 0.84 | CHRM1 (0.39) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Octadecanoic Acid Amide SCHEMBL2065217 | 0.83 | TP53 (0.37) | GRIK1GRIK2CYP3A4TSHRNFKB1 | |
| Tetradecanamide SCHEMBL2065731 | 0.83 | TP53 (0.37) | GRIK1GRIK2CYP3A4TSHRNFKB1 | |
| Palmitamide SCHEMBL2065209 | 0.83 | TP53 (0.37) | GRIK1GRIK2CYP3A4TSHRNFKB1 | |
| Glycinebetaine SCHEMBL2132643 | 0.79 | GPR84 (0.41) | CA2CA1SLC1A2SLC1A1GRIK1 | |
| Glycinebetaine SCHEMBL3889766 | 0.79 | GPR84 (0.41) | CA2CA1SLC1A2SLC1A1GRIK1 | |
| Glycinebetaine SCHEMBL2133338 | 0.79 | GPR84 (0.41) | CA2CA1SLC1A2SLC1A1GRIK1 | |
| Glycinebetaine SCHEMBL2135218 | 0.79 | GPR84 (0.41) | CA2CA1SLC1A2SLC1A1GRIK1 | |
| Glycinebetaine SCHEMBL2131138 | 0.79 | GPR84 (0.41) | CA2CA1SLC1A2SLC1A1GRIK1 | |
| Glycinebetaine SCHEMBL1065800 | 0.79 | GPR84 (0.41) | CA2CA1SLC1A2SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216559-B2 | Deodorant fiber and fibrous article and product made thereof | JNC CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20050255078-A1 | Deodorant fiber and fibrous article and product made thereof | CHISSO CORPOARTION (JP) | 2005-11-17 | — | — | US | disclosed |