Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 5/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634827 | 0.89 | C5AR1 (0.43) | ALDH1A1LMNAPTBP1PDK2UBE2M | |
| SCHEMBL6418906 | 0.81 | SLC6A4 (0.53) | UBE2MDCUN1D1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6418281 | 0.76 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL6418641 | 0.71 | GPR119 (0.46) | C5AR1 | |
| SCHEMBL6431531 | 0.67 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3KCNH2MCHR1 | |
| SCHEMBL4634065 | 0.67 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3KCNH2MCHR1 | |
| SCHEMBL6431527 | 0.67 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3KCNH2MCHR1 | |
| SCHEMBL6410766 | 0.67 | SLC6A4 (0.48) | PDK2UBE2MDCUN1D1SLC6A4SLC6A2 | |
| SCHEMBL6418851 | 0.66 | LMNA (0.48) | ALDH1A1LMNAPTBP1UBE2MDCUN1D1 | |
| SCHEMBL6414218 | 0.66 | CHRM2 (0.47) | UBE2MDCUN1D1SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | PFIZER INC | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | SLC6A4, HTR3C, HTR3A | ALDH1A1 1300/4885LMNA 3468/4885PTBP1 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.