Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429618 | 0.88 | LMNA (0.57) | LMNAPOLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1287564 | 0.83 | TDP1 (0.59) | LMNAPOLBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL5960054 | 0.83 | ALDH1A1 (0.68) | LMNAPOLBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL5165402 | 0.78 | GAA (0.64) | LMNAPOLBALDH1A1MAPK1HTT | |
| SCHEMBL8752443 | 0.78 | ALDH1A1 (0.55) | LMNAPOLBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL12491364 | 0.78 | SMN1; SMN2 (0.54) | LMNAALDH1A1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL5675703 | 0.78 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2L3MBTL1CA12 | |
| SCHEMBL407668 | 0.76 | CA12 (0.61) | LMNAPOLBALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7108847 | 0.75 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CA12CA9HTT | |
| SCHEMBL5166003 | 0.74 | SMN1; SMN2 (0.60) | LMNAALDH1A1SMN1; SMN2L3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193389-B2 | N-substituted benzene sulfonamides | ELAN PHARMACEUTICALS, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-20050245573-A1 | N-substituted benzene sulfonamides | ELAN PHARMACEUTICALS, INC. | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245573-A1 | N-substituted benzene sulfonamides | PSEN1, PSEN2, BCHE | LMNA 3051/4885POLB 3634/4885ALDH1A1 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.