Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419015 | 0.88 | LMNA (0.71) | LMNASMN1; SMN2L3MBTL1CA12CA9 | |
| SCHEMBL5164811 | 0.80 | GAA (0.55) | LMNASMN1; SMN2ALDH1A1POLBHTT | |
| SCHEMBL12491364 | 0.75 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2L3MBTL1CA12CA9 | |
| SCHEMBL498544 | 0.75 | MEN1 (0.43) | LMNAL3MBTL1CA12CA9ALDH1A1 | |
| SCHEMBL17861662 | 0.75 | CASR (0.43) | L3MBTL1CA12CA9CYP1A2CYP2C19 | |
| SCHEMBL8747424 | 0.74 | HTR6 (0.62) | CA12CA9KMT2A | |
| SCHEMBL407668 | 0.73 | CA12 (0.61) | LMNAL3MBTL1CA12CA9ALDH1A1 | |
| SCHEMBL7356282 | 0.73 | NPC1 (0.43) | LMNAL3MBTL1CA12CA9ALDH1A1 | |
| SCHEMBL1649916 | 0.73 | CA1 (0.50) | LMNACA12CA9ALDH1A1CYP1A2 | |
| SCHEMBL29469878 | 0.73 | CA1 (0.50) | LMNACA12CA9ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |