Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419987 | 1.00 | RAB9A (0.44) | RAB9ANPC1CTDSP1SMN1; SMN2MAPT | |
| SCHEMBL6419227 | 1.00 | RAB9A (0.44) | RAB9ANPC1CTDSP1SMN1; SMN2MAPT | |
| SCHEMBL6418420 | 0.98 | SMN1; SMN2 (0.44) | RAB9ANPC1CTDSP1SMN1; SMN2MAPT | |
| SCHEMBL4630812 | 0.89 | MTNR1A (0.48) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6438461 | 0.89 | SMN1; SMN2 (0.42) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL6438467 | 0.89 | SMN1; SMN2 (0.42) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL6438458 | 0.89 | SMN1; SMN2 (0.42) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL4631622 | 0.82 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2MAPTCHRNB2 | |
| SCHEMBL17802374 | 0.82 | CES2 (0.50) | MAPTL3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4631618 | 0.82 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2MAPTCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972294-B1 | Compounds, their preparation and use | NOVO NORDISK, A/S (DK) | 2005-12-06 | — | — | US | disclosed |
| EP-1171414-A1 | COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063153-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |