Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419600 | 1.00 | NR3C1 (0.33) | NR3C1PGRNR3C2TRPV1 | |
| SCHEMBL6419606 | 1.00 | NR3C1 (0.33) | NR3C1PGRNR3C2TRPV1 | |
| SCHEMBL3533377 | 0.92 | NR3C1 (0.36) | NR3C1PGRNR3C2 | |
| SCHEMBL3533375 | 0.92 | NR3C1 (0.36) | NR3C1PGRNR3C2 | |
| SCHEMBL3533373 | 0.92 | NR3C1 (0.36) | NR3C1PGRNR3C2 | |
| SCHEMBL6419608 | 0.85 | NR3C1 (0.36) | NR3C1PGRNR3C2 | |
| SCHEMBL4358212 | 0.80 | NR3C1 (0.35) | NR3C1PGRNR3C2 | |
| SCHEMBL4358215 | 0.80 | NR3C1 (0.35) | NR3C1PGRNR3C2 | |
| SCHEMBL4358218 | 0.80 | NR3C1 (0.35) | NR3C1PGRNR3C2 | |
| SCHEMBL3533643 | 0.76 | PGR (0.36) | NR3C1PGRNR3C2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272823-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272823-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | DHPS, TNF, PTGES | NR3C1 1000/4885PGR 3505/4885NR3C2 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.