Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60842 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EGAAPOLBHIF1A | |
| SCHEMBL8626899 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EGAAPOLBHIF1A | |
| SCHEMBL29387985 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EGAAPOLBHIF1A | |
| SCHEMBL9123978 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EGAAPOLBHIF1A | |
| SCHEMBL20510894 | 0.78 | KDM4E (0.40) | SMN1; SMN2KDM4EGAAPOLBALDH1A1 | |
| SCHEMBL30360770 | 0.78 | KDM4E (0.40) | SMN1; SMN2KDM4EGAAPOLBALDH1A1 | |
| SCHEMBL297297 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2GAAALDH1A1TSHRLMNA | |
| SCHEMBL6367706 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EGAAPOLBALDH1A1 | |
| SCHEMBL9746326 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EGAAPOLBHIF1A | |
| SCHEMBL21142943 | 0.76 | AR (0.48) | SMN1; SMN2KDM4EGAAPOLBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050196454-A1 | Poly(styrene-b-4-vinylphenoxyphthalonitrile) complexed with cobalt or other Group VIII metals; protective coatings | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 2005-09-08 | — | — | US | claimed |
| US-20050196454-A1 | Poly(styrene-b-4-vinylphenoxyphthalonitrile) complexed with cobalt or other Group VIII metals; protective coatings | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050196454-A1 | Poly(styrene-b-4-vinylphenoxyphthalonitrile) complexed with cobalt or other Group VIII metals; protective coatings | PPOX, PARN, PRNP | SMN1; SMN2 741/4885KDM4E 2072/4885GAA 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.