Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 6/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635601 | 0.85 | KDM4E (0.50) | SMN1; SMN2KDM4EPOLBGAATLR8 | |
| SCHEMBL18712911 | 0.84 | TLR8 (0.36) | SMN1; SMN2KDM4EPOLBGAATLR8 | |
| SCHEMBL9359794 | 0.81 | KDM4E (0.54) | SMN1; SMN2KDM4EPOLBGAATLR8 | |
| SCHEMBL20511067 | 0.81 | KDM4E (0.54) | SMN1; SMN2KDM4EPOLBGAATLR8 | |
| SCHEMBL9745662 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EPOLBGAATLR8 | |
| SCHEMBL9745478 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EPOLBGAATLR8 | |
| SCHEMBL30360768 | 0.81 | KDM4E (0.54) | SMN1; SMN2KDM4EPOLBGAATLR8 | |
| SCHEMBL669346 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL1362882 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EPOLBGAATLR8 | |
| SCHEMBL8975487 | 0.80 | POLB (0.73) | SMN1; SMN2KDM4EPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050196454-A1 | Poly(styrene-b-4-vinylphenoxyphthalonitrile) complexed with cobalt or other Group VIII metals; protective coatings | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050196454-A1 | Poly(styrene-b-4-vinylphenoxyphthalonitrile) complexed with cobalt or other Group VIII metals; protective coatings | PPOX, PARN, PRNP | SMN1; SMN2 741/4885KDM4E 2072/4885POLB 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.