Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419860 | 0.81 | ATM (0.47) | KIF11 | |
| SCHEMBL31404235 | 0.75 | KIF11 (0.50) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL12151786 | 0.74 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11KMT2A | |
| SCHEMBL20799447 | 0.74 | ALDH1A1 (0.50) | KIF11SLC6A1SLC6A11 | |
| SCHEMBL1895560 | 0.73 | SLC6A11 (0.51) | KIF11KCNH2SLC6A1SLC6A11KMT2A | |
| SCHEMBL13388489 | 0.72 | KIF11 (0.50) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL6707492 | 0.72 | SLC6A1 (0.49) | KIF11KCNH2SLC6A1SLC6A11KMT2A | |
| SCHEMBL26626984 | 0.72 | SLC6A1 (0.49) | KIF11KCNH2SLC6A1SLC6A11KMT2A | |
| SCHEMBL17423858 | 0.72 | KIF11 (0.50) | KIF11KCNH2SLC6A1SLC6A11KMT2A | |
| SCHEMBL20371097 | 0.72 | KIF11 (0.50) | KIF11KCNH2SLC6A1SLC6A11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165569-B1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES INC (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1165569-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | Agilent Technologies, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056740-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | PROLINX, INC. (US) | 2000-09-28 | — | — | WO | disclosed |
| US-6031117-A | Boronic acid containing phosphoramidite reagents | PROLINX INCORPORATED (US) | 2000-02-29 | — | — | US | disclosed |
| US-6013783-A | Boronic acid containing oligonucleotides and polynucleotides | PROLINX INCORPORATED (US) | 2000-01-11 | — | — | US | disclosed |