Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422607 | 0.87 | P2RX7 (0.43) | PTGDR2P2RX7FAAHPDK2 | |
| SCHEMBL6420064 | 0.87 | GRIN2B (0.38) | PTGDR2KMT2AP2RX7F13A1TGM2 | |
| SCHEMBL6423530 | 0.85 | PTGDR2 (0.36) | PTGDR2KMT2AP2RX7MEN1PDK2 | |
| SCHEMBL6424323 | 0.84 | P2RX7 (0.44) | P2RX7F13A1TGM2TGM1PDK2 | |
| SCHEMBL6422386 | 0.84 | CD274 (0.42) | EPHX1 | |
| SCHEMBL6423885 | 0.83 | PTGDR2 (0.37) | PTGDR2P2RX7FAAHF13A1TGM2 | |
| SCHEMBL6422824 | 0.79 | CHRM5 (0.41) | PTGDR2KMT2AP2RX7CHRM5CHRM1 | |
| SCHEMBL6420512 | 0.79 | GRIN2B (0.40) | FAAHCHRM5CHRM1 | |
| SCHEMBL6422626 | 0.79 | PTGDR2 (0.37) | PTGDR2KMT2AMEN1PDK2 | |
| SCHEMBL6420249 | 0.79 | PTGDR2 (0.36) | PTGDR2KMT2AP2RX7MEN1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |