Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422607 | 0.86 | P2RX7 (0.43) | P2RX7PDK2 | |
| SCHEMBL6420064 | 0.86 | GRIN2B (0.38) | P2RX7PDK2F13A1TGM2TGM1 | |
| SCHEMBL6420047 | 0.84 | PTGDR2 (0.37) | P2RX7PDK2F13A1TGM2TGM1 | |
| SCHEMBL6423530 | 0.82 | PTGDR2 (0.36) | P2RX7PDK2 | |
| SCHEMBL6422386 | 0.81 | CD274 (0.42) | — | |
| SCHEMBL6423885 | 0.79 | PTGDR2 (0.37) | P2RX7PDK2F13A1TGM2TGM1 | |
| SCHEMBL6422824 | 0.79 | CHRM5 (0.41) | P2RX7PDK2 | |
| SCHEMBL6422626 | 0.79 | PTGDR2 (0.37) | PDK2 | |
| SCHEMBL25285486 | 0.78 | TRPC5 (0.52) | P2RX7PDK2TRPC5 | |
| SCHEMBL6420249 | 0.78 | PTGDR2 (0.36) | P2RX7PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |