Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 13/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420311 | 0.84 | APP (0.47) | APP | |
| SCHEMBL3012099 | 0.78 | CYP3A4 (0.50) | APP | |
| SCHEMBL13008101 | 0.75 | IDO1 (0.32) | — | |
| SCHEMBL4496052 | 0.74 | PREP (0.48) | APP | |
| SCHEMBL3426875 | 0.72 | AGXT (0.32) | APP | |
| SCHEMBL14282994 | 0.71 | MAOB (0.47) | — | |
| SCHEMBL14282996 | 0.71 | MAPT (0.39) | — | |
| SCHEMBL16599423 | 0.71 | THRB (0.35) | PCNA | |
| SCHEMBL5778569 | 0.71 | USP14 (0.32) | — | |
| SCHEMBL9366384 | 0.71 | APP (0.40) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8352193-B2 | Methods for deriving a cumulative ranking | TARGET DISCOVERY, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2479578-A1 | Mass defect labeling for the determination of oligomer sequences | Target Discovery, Inc. (US) | 2012-07-25 | — | — | EP | disclosed |
| US-7316931-B2 | Mass defect labeling for the determination of oligomer sequences | TARGET DISCOVERY, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-20070154900-A1 | Methods for determining protein and peptide terminal sequences | TARGET DISCOVERY, INC (US) | 2007-07-05 | — | — | US | disclosed |
| US-6962818-B2 | Mass defect labeling for the determination of oligomer sequences | TARGET DISCOVERY (US) | 2005-11-08 | — | — | US | disclosed |