SCHEMBL6420573

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5921502	0.77	KDR (0.59)	KDRCDK2PRKCDAURKACHEK1
	SCHEMBL3756770	0.75	MAPK10 (0.70)	MKNK1MKNK2CDK2PRKCDIKBKB
	SCHEMBL27654819	0.75	MAPT (0.56)	MKNK1MKNK2KDRCDK2PRKCD
	SCHEMBL18803587	0.74	MKNK1 (1.00)	MKNK1MKNK2CDK2
	SCHEMBL148200	0.74	KDR (0.61)	MKNK1MKNK2KDRCDK2PRKCD
	SCHEMBL6715378	0.72	ALDH1A1 (0.50)	MKNK1MKNK2NPC1MAPTMAPK1
	SCHEMBL9520789	0.72	KDM4E (0.50)	NPC1MAPTMAPK1RAB9A
	SCHEMBL6795636	0.71	KDR (0.59)	MKNK1KDRCDK2PRKCDAURKA
	SCHEMBL22860794	0.71	POLB (0.61)	MKNK1KDRCDK2PRKCDAURKA
	SCHEMBL28118781	0.71	SMG1 (0.70)	CDK2AURKACDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.