Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.50 |
| ▸ | ACLY | P53396 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424798 | 0.85 | ACLY (0.45) | AGTR1ACLYHSD17B10FABP3FABP4 | |
| SCHEMBL6437617 | 0.85 | ACLY (0.43) | AGTR1ACLYHSD17B10FABP3FABP4 | |
| SCHEMBL3553704 | 0.85 | FABP3 (0.47) | AGTR1ACLYHSD17B10FABP3FABP4 | |
| SCHEMBL3929367 | 0.78 | AGTR1 (0.39) | AGTR1ACLYCYP2C19HTR6TSHR | |
| SCHEMBL3562959 | 0.78 | AGTR1 (0.57) | AGTR1ACLYHTR6L3MBTL1PSEN1 | |
| SCHEMBL3557485 | 0.76 | AGTR1 (0.58) | AGTR1ACLYHSD17B10FABP3FABP4 | |
| SCHEMBL14953639 | 0.76 | ACLY (0.57) | ACLYKMT2A | |
| SCHEMBL14953556 | 0.73 | ACLY (0.46) | ACLYHSD17B10FABP4CYP2C19HTR6 | |
| SCHEMBL3555537 | 0.72 | ACLY (0.38) | AGTR1ACLYCYP2C19HTR6 | |
| SCHEMBL3556363 | 0.71 | HTR6 (0.49) | ACLYHSD17B10FABP3FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | disclosed |
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |