Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 6/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FABP2 | P12104 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422478 | 0.85 | ACLY (0.41) | ACLYMCL1FABP3FABP4FABP5 | |
| SCHEMBL6420752 | 0.85 | AGTR1 (0.50) | ACLYAGTR1FABP3FABP4FABP5 | |
| SCHEMBL3553704 | 0.82 | FABP3 (0.47) | ACLYAGTR1FABP3FABP4FABP5 | |
| SCHEMBL14953515 | 0.77 | ACLY (0.54) | ACLYKMT2A | |
| SCHEMBL6820925 | 0.74 | BCL2 (0.40) | AGTR1MCL1CYP2C19HSD17B10LMNA | |
| SCHEMBL14953494 | 0.74 | ACLY (0.43) | ACLYFABP4HSD17B10HTR6NOD1 | |
| SCHEMBL3557485 | 0.74 | AGTR1 (0.58) | ACLYAGTR1FABP3FABP4FABP5 | |
| SCHEMBL6437617 | 0.70 | ACLY (0.43) | ACLYAGTR1FABP3FABP4FABP5 | |
| SCHEMBL3562443 | 0.68 | ACLY (0.50) | ACLYAGTR1HTR6LMNA | |
| SCHEMBL3556363 | 0.67 | HTR6 (0.49) | ACLYFABP3FABP4FABP5CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | disclosed |
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |