Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029934 | 0.92 | CYP1A2 (0.34) | CYP1A2CYP1B1CYP1A1CYP2A6PRKDC | |
| SCHEMBL6420832 | 0.88 | CYP2A6 (0.36) | CYP1A2CYP1B1CYP2A6HPRT1AHR | |
| SCHEMBL8056031 | 0.84 | CES1 (0.36) | CYP1A2CYP2A6HPRT1CES1ALDH1A1 | |
| SCHEMBL8022208 | 0.83 | CES1 (0.37) | CYP1A2CYP2A6HPRT1CES1ALDH1A1 | |
| SCHEMBL29447338 | 0.82 | ALDH1A1 (0.39) | CYP1B1CYP2A6HPRT1ALDH1A1HSD17B10 | |
| SCHEMBL3955072 | 0.82 | ALDH1A1 (0.39) | CYP1B1CYP2A6HPRT1ALDH1A1HSD17B10 | |
| SCHEMBL29695262 | 0.81 | ALDH1A1 (0.38) | CYP1B1CYP2A6HPRT1ALDH1A1HSD17B10 | |
| SCHEMBL6418430 | 0.81 | HPRT1 (0.38) | CYP1A2CYP1B1CYP1A1CYP2A6HPRT1 | |
| Potassium SCHEMBL29695394 | 0.80 | WDR5 (0.37) | CYP1B1CYP2A6HPRT1ALDH1A1HSD17B10 | |
| SCHEMBL8020531 | 0.78 | CYP2A6 (0.37) | CYP1A2CYP1B1CYP2A6HPRT1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | claimed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | claimed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | claimed |
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | disclosed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | disclosed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |