Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21054797 | 0.73 | PDE3B (0.41) | DAO | |
| SCHEMBL21250167 | 0.68 | PDE3B (0.33) | DAO | |
| SCHEMBL7702540 | 0.60 | DAO (0.55) | DAO | |
| SCHEMBL29410020 | 0.58 | GRIN1 (0.36) | DAO | |
| SCHEMBL28550669 | 0.58 | DAO (0.63) | DAO | |
| SCHEMBL1948642 | 0.58 | TYRO3 (0.44) | — | |
| SCHEMBL28906733 | 0.58 | ALDH1A1 (0.35) | DAO | |
| SCHEMBL31648205 | 0.56 | GAA (0.33) | — | |
| SCHEMBL17113560 | 0.56 | CA12 (0.35) | — | |
| SCHEMBL21053957 | 0.54 | LMNA (0.50) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004133-A1 | Modulators of VR1 receptor | VERTEX PHARMACEUTICALS INCORPORATED | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004133-A1 | Modulators of VR1 receptor | TRPV1, TRPV2, TRPV3 | DAO 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.