SCHEMBL642113

SCHEMBL642113

ClC(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
ALDH1A1 P00352 1/20 0.30
CYP2E1 P05181 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8157111 0.74 ALDH1A1 (0.41) ALDH1A1
SCHEMBL16499790 0.74
SCHEMBL5709482 0.74
SCHEMBL28732243 0.74
SCHEMBL20210862 0.74 TSHR (0.36) TSHR
Pentachloroethane SCHEMBL4728 0.71
SCHEMBL8089187 0.67 LMNA (0.39) LMNAALDH1A1CYP2E1TSHR
Pentachloroethane SCHEMBL11767822 0.67 LMNA (0.39) LMNAALDH1A1CYP2E1TSHR
SCHEMBL562402 0.63
SCHEMBL893157 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11918939-B2 Method for purifying hydrofluorocarbons ARKEMA FRANCE (FR) 2024-03-05 US claimed
US-20220297025-A1 METHOD FOR PURIFYING HYDROFLUOROCARBONS ARKEMA FRANCE (FR) 2022-09-22 US claimed
EP-4025314-A1 METHOD FOR PURIFYING HYDROFLUOROCARBONS ARKEMA FRANCE (FR) 2022-07-13 EP claimed
CN-114340753-A Process for purifying hydrofluorocarbons 阿科玛法国公司 2022-04-12 CN claimed
WO-2021043989-A1 METHOD FOR PURIFYING HYDROFLUOROCARBONS ARKEMA FRANCE (FR) 2021-03-11 WO claimed
CN-102964205-B One-kettle way preparation method of 2-hydro-1,1,1,2,3,3,3-heptachloropropane UNIV NANJING INF SCI & TECH 2014-05-14 CN claimed
CN-102617268-B Preparation of heptafluoropropane through gas phase catalysis fluorination ZHANG CHAOZHI 2014-02-05 CN claimed
CN-102491871-B Preparation method of heptafluoropropane UNIV NANJING INF SCI & TECH 2013-12-18 CN claimed
CN-102964205-A One-kettle way preparation method of 2-hydro-1,1,1,2,3,3,3-heptachloropropane UNIV NANJING INF SCI & TECH 2013-03-13 CN claimed
EP-1051377-A1 PRODUCTION OF HEPTAFLUOROPROPANE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2000-11-15 EP claimed
US-6087500-A Methods for producing pyrimidine compounds NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-07-11 US claimed
WO-1999040053-A1 PRODUCTION OF HEPTAFLUOROPROPANE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1999-08-12 WO claimed
EP-0902019-A1 PROCESSES FOR THE PREPARATION OF PYRIMIDINE COMPOUND NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1999-03-17 EP claimed
US-20240234031-A1 SEMICONDUCTOR DEVICE AND SEMICONDUCTOR APPARATUS AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-11 US disclosed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-04-23 US disclosed
EP-0457510-A2 Process for preparing carbon/carbon composite NIPPON OIL COMPANY, LIMITED (JP) 1991-11-21 EP disclosed
EP-0028430-B1 A PROCESS FOR THE ELECTROREDUCTIVE PREPARATION OF ORGANIC COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-01-18 EP disclosed
EP-0028430-A1 A process for the electroreductive preparation of organic compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-05-13 EP disclosed
US-4020063-A Oxadiazepine cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent L3MBTL3, L3MBTL1, L3MBTL4 LMNA 4405/4885ALDH1A1 1266/4885CYP2E1 70/4885
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent H1-3, HDAC3, H1-0 LMNA 4131/4885ALDH1A1 810/4885CYP2E1 293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.