Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 4/20 | 0.63 |
| ▸ | CASP6 | P55212 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NSD2 | O96028 | 5/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.44 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936983 | 0.97 | NT5E (0.63) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| Potassium Ion SCHEMBL7457856 | 0.89 | NT5E (0.47) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| Potassium Ion SCHEMBL29829524 | 0.89 | NT5E (0.47) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL29392802 | 0.89 | NT5E (0.73) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL151762 | 0.89 | NT5E (0.73) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL8968523 | 0.89 | NT5E (0.73) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL8713026 | 0.89 | NT5E (0.73) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL8008839 | 0.87 | NT5E (0.71) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL7457861 | 0.87 | NT5E (0.71) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| Water SCHEMBL28374688 | 0.87 | NT5E (0.71) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170279145-A1 | MULTI-ACID POLYMERS FROM MULTIFUNCTIONAL AMINO ACIDS AND SULFONYL HALIDE PRECURSORS AND METHODS OF MAKING THE SAME | NISSAN MOTOR CO., LTD. (JP) | 2017-09-28 | — | — | US | claimed |
| US-10930961-B2 | Multi-acid polymers from multifunctional amino phosphonic acids and sulfonyl halide precursors and methods of making the same | NISSAN NORTH AMERICA, INC. (US) | 2021-02-23 | — | — | US | disclosed |
| CN-110272882-B | Complex enzyme system for degrading wheat arabinoxylan and application thereof | 山东大学 | 2020-10-30 | — | — | CN | disclosed |
| US-10468701-B2 | Multi-acid polymers from multifunctional amino acids and sulfonyl halide precursors and methods of making the same | NISSAN NORTH AMERICA, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190013538-A1 | Multi-Acid Polymers From Multifunctional Amino Acids and Sulfonyl Halide Precursors and Methods of Making the Same | NISSAN MOTOR CO., LTD. (JP) | 2019-01-10 | — | — | US | disclosed |
| US-10153505-B2 | Multi-acid polymers from multifunctional amino acids and sulfonyl halide precursors and methods of making the same | NISSAN NORTH AMERICA, INC. (US) | 2018-12-11 | — | — | US | disclosed |
| US-10035144-B2 | Multi-acid polymers and methods of making the same | NISSAN NORTH AMERICA, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20180036995-A1 | HYDROPHILIC MONOLAYER FILM WITH OPTICAL FUNCTIONALITY AND STACK OF THE SAME | MITSUI CHEMICALS, INC. (JP) | 2018-02-08 | — | — | US | disclosed |
| EP-3270192-A1 | HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF | Mitsui Chemicals, Inc. (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-9861977-B2 | Multi-acid polymers and methods of making the same | NISSAN NORTH AMERICA, INC. (US) | 2018-01-09 | — | — | US | disclosed |
| US-6966213-B2 | Rapid method for detecting leaks of hydraulic fluids in production plants | NALCO COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-20050160795-A1 | Rapid method for detecting leaks of hydraulic fluids in production plants | ECOLAB USA INC. | 2005-07-28 | — | — | US | disclosed |
| US-20020193515-A1 | Polarization film containing a monoazo compound or salt | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-19 | — | — | US | disclosed |
| US-6399752-B1 | PHOTOSTABILITY; HEAT RESISTANCE; WATERPROOFING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-0388356-B1 | Ultraviolet absorbing lenses and methods of making the same | CIBA GEIGY AG (CH) | 1998-07-08 | — | — | EP | disclosed |
| EP-0538969-B1 | Composition and method for inhibiting scale and corrosion using naphthylamine polycarboxylic acids | BETZDEARBORN INC (US) | 1998-05-27 | — | — | EP | disclosed |
| US-5284558-A | Treating a labelled and charged oligosaccharide with an exoglycosidase to remove the non-reducing monosaccharide; correlating the enzyme specificity with electrophoretic data | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0538969-A2 | Composition and method for inhibiting scale and corrosion using naphthylamine polycarboxylic acids | W.R. Grace & Co.-Conn. (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5139702-A | Scale and corrosion inhibitors | W. R. GRACE & CO.-CONN. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0388356-A2 | Ultraviolet absorbing lenses and methods of making the same | CIBA-GEIGY AG (CH) | 1990-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035144-B2 | Multi-acid polymers and methods of making the same | INSR, IAPP, SLC5A6 | NT5E 4020/4885CASP6 2266/4885ALDH1A1 3403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.