SCHEMBL6421760

SCHEMBL6421760

C=Cc1ccc(C(=O)C(C)(O)CC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.46
TAS1R1 Q7RTX1 2/20 0.46
ALDH1A1 P00352 1/20 0.39
THRB P10828 6/20 0.38
THRA P10827 5/20 0.38
MLYCD O95822 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA2 P00918 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
SLC6A4 P31645 1/20 0.32
EPHX2 P34913 1/20 0.32
NR1H4 Q96RI1 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL803878 0.83 ALDH1A1 (0.44) TAS1R3TAS1R1ALDH1A1THRBTHRA
SCHEMBL13838707 0.81 TAS1R3 (0.43) TAS1R3TAS1R1ALDH1A1THRBTHRA
SCHEMBL10001141 0.81 ALDH1A1 (0.46) TAS1R3TAS1R1ALDH1A1THRBTHRA
SCHEMBL8589670 0.81 ALDH1A1 (0.38) ALDH1A1MLYCDTDP1MEN1KMT2A
SCHEMBL10782676 0.78 ALDH1A1 (0.42) TAS1R3TAS1R1ALDH1A1THRBTHRA
SCHEMBL4468555 0.77 CA2 (0.55) ALDH1A1TDP1CA2MEN1KMT2A
SCHEMBL4457411 0.76 ALDH1A1 (0.55) TAS1R3TAS1R1ALDH1A1TDP1
SCHEMBL10710582 0.76 HDAC1 (0.52) ALDH1A1TDP1EPHX2NR1H4MEN1
SCHEMBL7071203 0.75 TAS1R3 (0.41) TAS1R3TAS1R1ALDH1A1THRBTHRA
SCHEMBL195379 0.75 CES1 (0.50) ALDH1A1TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353265-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-20 US claimed
US-12391014-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2025-08-19 US claimed
EP-4532187-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-04-09 EP claimed
US-20230382065-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 US claimed
WO-2023228106-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
US-20250353265-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-20 US disclosed
US-12391014-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2025-08-19 US disclosed
EP-4532187-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-04-09 EP disclosed
US-20230382065-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 US disclosed
WO-2023228106-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO disclosed
CN-105152898-B Phenylbutanone derivative and application of same as photoinitiator 杭华油墨股份有限公司 2017-04-26 CN disclosed
CN-105152898-A Phenylbutanone derivative and application of same as photoinitiator HANGZHOU TOKA INK CO LTD 2015-12-16 CN disclosed
US-20050221095-A1 Hard coating agent and film with hard coating LINTEC CORPORATION (JP) 2005-10-06 US disclosed
EP-1216142-A4 THERMOFORMABLE OPHTHALMIC LENS NOVARTIS AG (CH) 2003-06-11 EP disclosed
EP-1216142-A1 THERMOFORMABLE OPHTHALMIC LENS Wesley Jessen Corporation (US) 2002-06-26 EP disclosed
WO-2001005578-A1 THERMOFORMABLE OPHTHALMIC LENS WESLEY-JESSEN CORPORATION (US) 2001-01-25 WO disclosed